- Author
- Year
- 2010
- Title
- Reduced context effects on retrieval in first-episode schizophrenia
- Journal
- PLoS ONE
- Volume | Issue number
- 5 | 4
- Article number
- e10356
- Number of pages
- 7
- Document type
- Article
- Faculty
- Faculty of Medicine (AMC-UvA)
Faculty of Social and Behavioural Sciences (FMG) - Institute
- Psychology Research Institute (PsyRes)
- Abstract
-
Background: A recent modeling study by the authors predicted that contextual information is poorly integrated into episodic representations in schizophrenia, and that this is a main cause of the retrieval deficits seen in schizophrenia.
Methodology/Principal Findings: We have tested this prediction in patients with first-episode schizophrenia and matched controls. The benefit from contextual cues in retrieval was strongly reduced in patients. On the other hand, retrieval based on item cues was spared.
Conclusions/Significance: These results suggest that reduced integration of context information into episodic representations is a core deficit in schizophrenia and one of the main causes of episodic memory impairment. - URL
- go to publisher's site
- Language
- English
- Persistent Identifier
- https://hdl.handle.net/11245/1.336028
- Downloads
-
journal.pone.0010356(Final published version)
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